Microsoft Word - Queuosine paper-26th March 2011

Tatsiana Rakovich‡, Coilin Boland‡, Ilana Bernstein § , Vimbai M. Chikwana ¶ , Dirk Iwata-Reuyl ¶ , and Vincent P. Kelly‡ From the ‡School of Biochemistry & Immunology, Trinity College Dublin, Dublin 2, Ireland, § School of Environmental & Life Sciences, University of Newcastle, Callaghan, NSW, 2308, Australia, and ¶ Department of Chemistry, Portland State University, Portland, Oregon 97207 Running head: Queuosine deficiency leads to elevated dihydrobiopterin Address correspondence to: Vincent Kelly, Ph.D., School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland. Tel: +353-1-8963507; Fax: 81-298-53-7318; E-mail: [email protected]